Head of otorhinolaryngology department
Speciality: Otorhinolaryngologist, Surgical oncologist
Title: M.D., Ph.D, Candidate of Medical Sciences
E-mail: This email address is being protected from spambots. You need JavaScript enabled to view it., This email address is being protected from spambots. You need JavaScript enabled to view it.
Phone: +375 (212) 57-40-01.
Department of Otorhinolaryngology, Vitebsk State Medical University, Frunze Str., 27 210000 Belarus
Vitebsk Clinics Emergency Hospital, Belarus,
Frunze Str., 71 210000 Belarus
Member of Belgian Oto-Rhino-Laryngology and Head and Neck Surgery Society (VA-NKO)
Member of European Laryngeal Society
SHORT SUMMARY
From September 2020 is a Head of Otorhinolaryngology Department at Vitebsk State Medical University
From October 2017 to August 2020 worked as an associate professor in otorhinolaryngology at Vitebsk State Medical University in Belarus.
Her comparative advantage is in bringing together extensive practical experience as an ENT surgeon and the cutting edge research at otorhinolaryngology.
In 2017, I have obtained Ph.D. in Medicine at the Department of Otorhinolaryngology at Ghent University (public defense the 10th of October 2017). PhD has been conducted a prestigious Erasmus Mundus WEBB Fellowship from the European Union of which I am the only recipient in medicine. I was studying under prominent professors of otorhinolaryngology and speech therapy. Sofie Claeys who is a Professor in Laryngology and the Head of Clinic of Otorhinolaryngology was my main tutor for research work. Professor Kristiane Van Lierde who is the Head of the Master Program of Logopedic and Audiological Sciences University Gent, Speech, Language Pathologist. My Ph.D. thesis is at the frontier of the otorhinolaryngology as it essentially bridges the gap between neuroscience/brain studies and the classic ENT issues. This research resulted in a number of published and under review papers in the leading international field journals and international conferences and holds promise for potentially significant improvements in the quality of patient care on the studied issue.
From 2016 until 2017 I have worked as a study physician acting as an investigator in clinical trials at the Upper Airways Research Laboratory (URL) Clinical trial center at the University Hospital Gent at the Department of Otorhinolaryngology (head: Professor Claus Bachert).
I combine this experience with the classical Russian school ENT training that I received while getting my Specialist Training and Candidate of Sciences in Medicine degree in Belarus. In my Candidate of Medical Sciences thesis, I have developed a polymer implant and method for rhinoplasty that was implemented as a standard in the nationwide clinical practice in Belarus and resulted in five patents. My results were broadly profiled in the national media and TV.
I am a fluent English speaker and a native Russian/Belarusian speaker. I have intermediate level of Ukraine. I understand basic Polish and Dutch (Certificate A2).
MEDICAL AND ACADEMIC DEGREES
2013–2017 | Ph.D. in Medicine |
Thesis “Functional magnetic resonance imaging study of central neural system control of voice, with emphasis on phonation in healthy women and women with muscle tension dysphonia” Tutor: Professor S.Claeys Faculty of Medicine and Health Sciences, Department of Otorhinolaryngology, Ghent University, Belgium |
2004–2008 |
Candidate of Medical Sciences GPA: 5.0/5.0 |
Thesis “A method of septoplasty using a synthetic mesh implant” Tutor: Professor V. Kunitsky Department of Otorhinolaryngology, Vitebsk State Medical University, Belarus |
2002–2007 | Senior Fellow, Fellow, Resident |
Specialization: Otorhinolaryngology Department of Otorhinolaryngology, Vitebsk State Medical University, Belarus |
1996– 2002 | M.D. (with the highest honors) | Vitebsk State Medical University, Belarus |
EDUCATION (COURSES, POSTGRADUATE TRAINING, CERTIFICATIONS)
Period |
University |
Courses and Postgraduate Training |
Certifications |
07.07.2019-13.07.2019 |
Weill Cornell Medicine-NYP General Hospital Salzburg |
Otology & Temporal Bone Surgery CD: Samuel Selesnick, MD Co-CD: Gerd Rasp, MD |
Certificate |
01.22.2019 – 25.05.2019 |
Department of Oncology, Belarusian Medical Academy of Postgraduate Education |
Surgical oncologist training course and Examination |
Diploma |
20.10.2016 |
University of Ghent, Belgium |
The Profess Basic ICH GCP Qualification training course and Examination |
Certificate |
31.08. 2015 – 01.09.2015 |
Department of otorhinolaryngology, Ghent University, Belgium |
Septorhinoplasty Workshop Tutor: Professor S. Claeys |
Certificate |
August 26 - 29, 2015 |
Ghent, Belgium |
27th International Course on Endoscopic Surgery of the Paranasal Sinuses and Skull Tutor: Professor C. Bachert |
An auditor |
August 27 - 30, 2014 |
Ghent, Belgium |
26th International Course on Endoscopic Surgery of the Paranasal Sinuses & Skull Base Tutor: Professor C. Bachert |
An auditor |
20.10.2005 – 19.12.2005 |
Ministry Of Health Of The Republic Of Belarus, Centre For Expertise and Testing in Health Care, Minsk, Belarus |
Training in international rules of Good Clinical Practice Tutor: Professor G. Godovalnikov |
Certificate |
01.10.2002 – 30.08.2007 |
Department of Otorhinolaryngology, Vitebsk State Medical University and Vitebsk Regional Clinical Hospital, Belarus |
Otorhinolaryngology training course and Board Examination Professor V. Kunitsky |
Certificate |
WORK EXPERIENCE/EMPLOYMENT
2017 - current |
Department of Otorhinolaryngology, Vitebsk State Medical University and Vitebsk Clinics Emergency Hospital, Belarus |
Associate Professor of otorhinolaryngology Specialist in Otorhinolaryngology |
2013 - 2017 |
Department of Otorhinolaryngology, Ghent University, Belgium |
PhD in Medicine, investigator |
2007 - 2013 |
Department of Otorhinolaryngology, Vitebsk State Medical University and Vitebsk Regional Clinical Hospital, Belarus |
Senior Fellow Specialist in Otorhinolaryngology (Cathedral Assistant) |
2002 - 2007 |
Department of Otorhinolaryngology, Vitebsk State Medical University and Vitebsk Regional Clinical Hospital, Belarus |
Fellow, Resident, Candidate of Medical Sciences |
CLINICAL SKILLS, TECHNIQUES, AND EXPERIENCE | Years of experience | |
Inpatient/outpatient care |
Ears, Nose, Throat Pathology |
17 |
Duty and urgency |
Ears, Nose, Throat Pathology |
3 |
Functional magnetic imaging (FMRI) |
Neurolaryngology, Vocal disorders |
3 |
Auditory evoked potentials (AEPs, P300) |
Neurolaryngology, Vocal disorders |
3,5 |
Clinical trials |
Upper Airways Research Laboratory (URL) Clinical trial center at the University Hospital Gent at the Department of Otorhinolaryngology (head: Professor C. Bachert). |
1 |
RECENT ADVANCED CLINICAL EXPERIENCE
2017 - current |
I am working as Associate Professor in Otorhinolaryngology at Vitebsk Clinics Emergency Hospital, Belarus. The main profiles are: neurolaryngology, general otorhinolaryngology and emergency ENT. |
2016 - 2017 |
GCP, clinical trials |
2013 – 2017 |
Neurolaryngology, Functional magnetic resonance imaging (fMRI); Auditory evoked potentials (AEPs). Videostrobolaryngoscopy; Rhinoscopy; Interpreting fMRI data (functional organization of the human brain): maps, modules and dimensions using Brain Voyager Software Creating and Organization of the large-scale neuronal networks of the human brain for creating advanced model of diagnostic and therapy of vocal disorders |
2007 – 2013
|
I worked as a “specialist doctor” at Vitebsk Regional Clinical Hospital, Belarus. The ENT department has 60 beds. The main profiles were: general otorhinolaryngology and emergency ENT. |
CURRENT RESEARCH
Department of Otorhinolaryngology at Vitebsk State Medical University
Research project: Immune function after surgery on the sinonasal area (septoplasty, ethmoid, sphenoid, and maxillary sinus surgery, turbinate surgery): the effect of postoperative treatment
Neurolaryngological Evaluation Of Voice Disorders
Major publications and work in progress for current research
Van Lierde*, M. Kryshtopava*, G. Van Maele, B. Boehme, N. Piens, K. Vonck “Impact of vagal nerve stimulation on objective vocal quality, a pilot study” Journal of Voice, 29.6 (2015): 777-e9.
*equal contribution
Kryshtopava, K. Van Lierde, I. Meerschman, E. D’Haeseleer, P. Vandemaele, G. Vingerhoets, S. Claeys “Functional Magnetic Resonance Imaging Study of Brain Activity Associated With Pitch Adaptation During Phonation in Healthy Women Without Voice Disorders”. Journal of Voice; 31:118 (2017): e121-118. e128.
D'haeseleer E., Behlau M., Bruneel L., Meerschman I., Luyten A., Lambrecht S., Cassol M., Corthals P., Kryshtopava M., Wuyts F.L., Claeys S., Van Lierde K. “Factors Involved in Vocal Fatigue: A Pilot Study”. Folia Phoniatrica et Logopaedica, 68 (2016): 112-118.
Kryshtopava M, Van Lierde K, Meerschman I, et al. Brain Activity During Phonation in Women With Muscle Tension Dysphonia: An fMRI Study. Journal of Voice. 2017 Apr 11. pii: S0892-1997(16)30505-7. doi: 10.1016/j.jvoice.2017.03.010.
Kryshtopava M., Van Lierde K., Defrancq C.; De Moor M.; Thijs Z.; Meerschman I., Vandemaele P., Vingerhoets G., and Claeys S. (2017). Brain activity during phonation in healthy female singers with supraglottic compression: an fMRI pilot study. Logopedics Phoniatrics Vocology, 1-10.
Kryshtopova M., Delendik IM, Solkin AA, Belyavsky N.N., Petrova L.G. Development of protocols for studying the role of the central nervous system in the control of voice formation in healthy individuals and patients suffering from functional dysphonia, and assessment of their effectiveness. “Otolaryngology. Eastern Europe "2018, volume 8, No 4 361-368.
Kryshtopava M., Van Lierde K., Claeys S. “Laryngeal neural control of phonation and functional voice disorders” (in progress).
Oral presentations
Kryshtopava, K. Van Lierde, I. Meerschman, E. D’Haeseleer, P. Vandemaele, G. Vingerhoets, S. Claeys "Neurophysiological foundation of human phonation: a pilot fMRI study”. Oral presentation. The Third Polish Lithuanian ENT Congress on September 26, 2015, Augustow (Poland)
Van Lierde, M. Krystopava, G. Van Maele, B. Boehme, N. Piens, K. Vonck "Impact of Nervus vagus stimulation on objective vocal quality, a pilot study". Oral presentation. Care of the professional voice, 27-31 05/2015, Philadelphia (USA).
Kryshtopava, K. Van Lierde, S. Claeys How talented is your voice? Oral presentation. Science Day, November, 2015, Ghent (Belgium).
Kryshtopava, K. Van Lierde, I. Meerschman, E. D’Haeseleer, P. Vandemaele, G. Vingerhoets, S. Claeys “Brain Mapping of Laryngeal Sensorimotor Control in Normal Phonation” Oral presentation. The 10th International Conference on Voice Physiology and Biomechanics, March 14 - 17, 2016, Viña del Mar (Chile)
Kryshtopava, K. Van Lierde, I. Meerschman, E. D’Haeseleer, S. Claeys “Functional magnetic resonance imaging study of brain activity during phonation in women with functional voice disorders” Oral presentation, Research Day, 16.03.2016, Ghent (Belgium
Meerschman, E. D‟Haeseleer, S. De Ley, M. Krystopava, S. Claeys, K.Van Lierde “Muscle Tension Dysphonia” Oral presentation. Symposium ‘Voice and Muscle Tension’ 16/04/2016, Brugge (Belgium)
Kryshtopava, M. De Moor, E. D’Haeseleer, K. Van Lierde, S. Claeys “Brain activity during phonation in healthy women with singing experience: an fMRI pilot study” Poster presentation. Studenten OnderzoeksSymposium (SOS), 26.04.2016, Ghent (Belgium) – Best poster presentation award!
Kryshtopava, K. Van Lierde, I. Meerschman, E. D’Haeseleer, P. Vandemaele, G. Vingerhoets, S. Claeys “Functional Magnetic Resonance Imaging Study of Brain Activity During Phonation In Women With Muscle Tension Dysphonia” Poster presentation, Knowledge for Growth, 6 May 2016 Ghent (Belgium).
Kryshtopava, K. Van Lierde, I. Meerschman, E. D’Haeseleer, G. Vingerhoets, S. Claeys "Central Neural Correlates Of Laryngeal Tension During Phonation In Muscle Tension Dysphonia: A Functional Magnetic Resonance Imaging Study” Oral presentation, 12th Salzburg Voice Symposium, brain & voice, 26 – 28 August, 2016 (Austria).
De Francq C.; De Moor M.; Thijs Z.; Kryshtopava M.; D’Haeseleer E.; Meerschman I.; Van Lierde K.; Vingerhoets G.; Claeys S. "Brain activity during phonation in healthy women with singing experience: an fMRI pilot study ” Oral presentation, 12th Salzburg Voice Symposium, brain & voice, 26 – 28 August, 2016 (Austria).
Van Lierde, M. Krystopava, S. Gadeyne, A. Luyten, E. Dhaseleer, L. Bruneel, G. Van Maele, B. Boehme, N. Piens, K. Vonck Impact of vagal nerve stimulation on objective vocal quality: a pilot study” Oral presentation 24 august 2016 Dublin, 30th World Congress of the IALP (Ireland)
Van Lierde, M. Behlau, E. Dhaeseleer, L. Bruneel, I. Meerschman, A. Luyten, S. lembrecht, M. Cassol, P. Corthals, M. Krystopava, F. Wuytens, S. Claeys “Factors involved in vocal fatique: a pilot study” Oral presentation 24 august 2016 Dublin, 30th World Congress of the IALP (Ireland)
Kryshtopava, K. Van Lierde, I. Meerschman, E. D’Haeseleer, G. Vingerhoets, S. Claeys "Functional magnetic resonance imaging study of central neural system control of voice, with emphasis on phonation in women with muscle tension dysphonia”. Oral presentation, Royal Belgian Society for Ear, Nose, Throat, Head and Neck Surgery Spring Symposium 25 March 2017, Brussels, Belgium
Maryna Kryshtopava, Kristiane Van Lierde, Iris Meerschman, Evelien D’Haeseleer, Sofie Claeys "Functional magnetic resonance imaging study of central neural system control of voice, with emphasis on phonation in women with muscle tension dysphonia" 12th Congress of the ELS in London (16.05.2018-19.05.2018)
Maryna Kryshtopava, Kristiane Van Lierde, Nikalay Byalyauski, Sofie Claeys "Voice imaging: approaches and protocols». 12th Congress of the ELS in London (16.05.2018-19.05.2018) (Neurolaryngology Award)
Kryshtopava M., Semenau S., Yakubcou N., Syatkouskaya Y. (Vitebsk) - Adaptation and Validation of the Sino-Nasal Outcome Test 20 (SNOT-20) XXX Marius Plouzhnikov International Conference of Young Otorhinolaryngologists, Saint Petersburg, 23.05.2018
Kryshtopava M., Yakubcou M., Syatkouskaya Y., Semenau S. Adaptation and validation of the sino-nasal outcome test 22 (SNOT-22) into Russian, SERIN 2018, October 23-25, 2018, P9
Syamenau S., Kulyakin Y., Aleksandrovsky K., Sjatkovskaya Y., Kryshtopava M. Comparative analysis of the effectiveness of surgical treatment of vasomotor rhinitis, SERIN 2018, October 23-25, 2018, P10
Kryshtopova MA, Zatoloka AP, Lesun ON, Kovalyonok EV, Semenov SA, Yakubtsov N.А. Assessment of the quality of life in patients with chronic rhinosinusitis. Annual autumn conference of otorhinolaryngologists of the Republic of Belarus with international participation, November 16, 2018, Minsk, Belarus.
Krishtopova M., Osipuk E.S., Delendik I.M., Belyavsky N.N., Petrova L.G. Analysis of cognitive auditory evoked potentials (P300) in patients with functional dysphonia. Annual autumn conference of otorhinolaryngologists of the Republic of Belarus with international participation, November 16, 2018, Minsk, Belarus.
Kryshtopova M., Belyavsky N.N., Petrova L.G. «The evaluation of cognitive function in functional dysphonia» The 5th Congress of European ORL-Head & Neck Surgery, 29.06 - 03.07.2019, Brussels, Belgium, poster presentation.
Kryshtopava M, Van Lierde K, Byalyauski N., Petrova L., Claeys S. “Functional dysphonia: Why do we use protocol of the European Laryngological Society (ELS) with extensions?” 5th Lithuanian - Polish ENT Congress June 13-15, 2019. Druskininkai, Lithuania
ADDITIONAL RESEARCH AREAS
Tissue engineering of cartilage for craniofacial and neck reconstruction (flexible cartilage for ear, nose and larynx); cartilaginous tissue healing; biomaterials.
2008
A method of septoplasty using a synthetic mesh implant. Thesis: Degree of Candidate of Medical Sciences, Vitebsk State Medical University, Belarus
2002
Efficiency of a hormone replacement therapy after thyroidectomy. Thesis: Degree of Doctorate of Medicine, Vitebsk State Medical University, Belarus.
PATENTS
- “Device for obtaining cartilage tissue layer slices” (Belarus #3137, 2006);
- “Implant” (Belarus # 3938, 2007);
- “Nasal tampon” (Belarus #3822, 2007);
- “A method for the reconstruction of the deformed nasal septum” (Belarus #12702; 2009);
- “The method of surgical treatment of the deformation of the nasal septum” (Belarus #12819, 2010);
CLINICAL TRAILS AND IMPLEMENTATION IN PRACTICE FOR DEVELOPED MATERIALS AND METHODS
- “A textile material for reconstruction of cartilage and bone structures”. Nationwide Clinical Trials completed in 2008, implemented in clinical practice, Belarus.
- “Septoplasty of nasal septum with reconstructed cartilage”. Recommended as a standard in Nationwide Clinical Practice starting from 2007, implemented in clinical practice.
- “Allotransplantation of parathyroid glands to treat severe forms of hypoparathyreosis”. Recommended to and implemented in clinical practice starting from 2001.
MAJOR HONORS AND AWARDS
- European laryngeal Society Neurolaryngology Award in 2018;
- Erasmus Mundus WEBB Fellowship The only recipient in medicine. International selection was conducted by European Union in all fields of sciences and humanities. Amount of award: a three-year stipend of Euro 54,000 (total) and full tuition and fees.
- National Prize (First place) “Best Innovation Project by Young Researchers” Country’s most prestigious prize for innovations done by researchers under age 35 in all fields of science and engineering. The prize is awarded for “Developing, business strategy, and implementation in clinical practice of the new biotechnological medical Textile Material for Reconstruction of Bone and Cartilage Structures”
- Second place Award of the President of the Republic of Belarus Country’s most prestigious prize for young researchers.The only recipient in medicine. Nationwide selection was conducted in all fields of sciences and humanities..
- Second place National Prize for Student Research The only recipient in medicine. Nationwide selection was conducted by the Ministry of Education in all fields of sciences and humanities.
REFERENCES
Professor Anatoliy Shchastniy | Professor in Surgery, Rector of Vitebsk State Medical University, Vitebsk, Belarus, This email address is being protected from spambots. You need JavaScript enabled to view it. |
Professor Sushkov Sergey | Vice-rector of Scientific and Research Affairs Candidate of Medical Science, associate, This email address is being protected from spambots. You need JavaScript enabled to view it. |
Professor Sofie Claeys | Professor in Laryngology, Head of Clinic of Otorhinolaryngology, Ghent University, This email address is being protected from spambots. You need JavaScript enabled to view it. |
Professor Hubert Vermeersch | Head of the Department of Head, Neck and Maxillofacial Surgery, Plastic Surgeon, Ghent University, This email address is being protected from spambots. You need JavaScript enabled to view it. |
Professor Kristiane Van Lierde | Head of the Master Program of Logopaedic and Audiological Science University Ghent, Speech, Language Pathologist, This email address is being protected from spambots. You need JavaScript enabled to view it. |
Professor Claus Bachert | Head of URL Clinical trial center at the UZ Gent, This email address is being protected from spambots. You need JavaScript enabled to view it. |